MycoCore 5
A Mushroom Complex Formula. That can reduce Fatigue, Stress & Anxiety and improve Sleep Quality.
The Science Behind MycoCore 5
MycoCore5 is a five -mushroom component of Fibro-Shakes, a carefully selected blend created to bring the nutritional diversity of five distinctive mushroom species into one simple, plant -based shake. Rather than building Fibro-Shakes around a long list of complicated supplements, MycoCore gives us a straightforward way to incorporate mushroom-derived ingredients into the everyday nutritional formula.
​
MycoCore 5 is a mushroom complex combining five strains - Cordyceps militaris, Ganoderma lucidum (Reishi), Hericium erinaceus (Lion's Mane), and Lentinula edodes (Shiitake), and Lentinula edodes. In a third-party twelve week randomized, double-blind, placebo controlled clinical trial, this combination demonstrated statistically significant improvements across three core domains: fatigue reduction, sleep quality, and stress resilience.
Fatigue Reduction
-9.2%
​
in 12 weeks
Sleep Quality
-11.1%
PSQI at 12 wks
Anxiety
Reduction
-33.5%
HAM-A at 12 wks
Cortisol
-5.5%
at 12 Weeks
Fatigue Reduction
Fatigue affects up to 80% of individuals, and it is considered one of the core symptoms of the condition and is closely linked to elevated inflammatory markers and dysregulated stress hormones. MycoCore 5 seemed to target both pathways and has shown to reduce systemic inflammation while restoring healthy norepinephrine levels for sustained energy without stimulants.
Biochemical Markers — Week 12
C-reactive protein (CßP) is a well-established marker of systemic inflammation. Elevated CRP correlates with fatigue severity across multiple conditions, from chronic fatigue syndrome to post-viral syndromes. the combination reduced CRP by 6.3%, while the placebo group saw a 4.9%increase — a net dfference of 11.2 percentage points. Norepinephrine, the neurotransmitter that sustains alertness and physical energy, rose 10.4% in the combination group compared to a slight decline (-0.8%) in placebo.
Subjective Fatigue Scores, Week 6
Using the Multidimensional Fatigue Inventory (MFI), participants reported meaningful reductions in both physical and general fatigue after just six weeks of supplementation. Physical fatigue improved up to 9.2% nearly four times the placebo response while general fatigue decreased 3.9%, roughly double the placebo improvement of 2%.
Sleep Qualty Improvement
Poor sleep affects nearly one in three adults, and the consequences cascade into every area of health immune function, cognitive performance, mood regulation, and metabolic health. this combination supports the body's natural sleep architecture by enhancing melatonin production and improving overall sleep quality as measured by the Pittsburgh Sleep Quality Index (PSQI).
Third-party study summary: Melatonin increased 3.9% by Week 12 — 70% greater than placebo (2.3%). Meanwhile, PSQI scores improved 11.1% by Week 12, representing over 10× the placebo response (-1.0%). Positive trends in melatonin appeared after just 6 weeks of supplementation.
Stress, Depression & Anxiety Reduction
The hypothalamic-pituitary-adrenal (HPA) axis governs the body's stress response. Chronic stress keeps cortisol and ACTH elevated, driving anxiety, depression, and burnout. this combination modulates the HPA axis at multiple points, lowering stress hormones and signifcantly reducing anxiety as measured by the gold-standard Hamilton Anxiety Rating Scale (HAM-A).
Stress Hormone Regulation
Third-party study summary. Serum cortisol, the body's primary stress hormone decreased 5.5% by Week 12 in this combination group, while placebo levels actually rose 0.8% over the same period. The upstream regulator ACTH (adrenocorticotropic hormone) showed an even faster response, dropping 10.5%by Week 6 the earliest biochemical signal of HPA-axis modulation.
​
Anxiety Reduction -HAM -A Scale
The Hamilton Anxiety Rating Scale is the gold-standard clinican-administered assessment for anxiety severity. Both groups improved over the 12-week trial, but the combination group showed a substantially larger reduction at every timepoint.
Why MycoCore5?
​
Five selected mushroom species
Cordyceps, Reishi, Lion's Mane, Maitake and Shiitake.
Standardized mushroom ingredient
Designed to provide consistency in important mushroom components from batch to batch.
Integrated into Fibro-Shakes
No separate mushroom supplement or additional step in your routine.
Caffeine-Free
The mushroom blend does not rely on caffeine or stimulant ingredients. Food-Based Approach
MycoCore5 is included as part of the broader nutritional composition of Fibro-Shakes rather than being presented as a treatment for a medical condition.
Dosage & Safety
Recommended dose: 500mg every other day with food.
• Standardized to >30% beta-glucans and
>5% triterpenes.
• No serious adverse events reported in the
12-week trial.
• Mild GI discomfort in <4% of participants,
resolving within one week.
Non-GMO, gluten -free, and produced in a
cGMP -certified facility.
• Third-party tested for heavy metals,
pesticides, and microbal contamination.
• Not recommended during pregnancy or for nursing mothers
Ready to experience the difference?
• Visit www.fibro-shakes.com to access the full benefits, · Available in Single. Duo Packs. & Quad Packs · Questions? Visit FAQ
​
These statements have not been evaluated by the Food and Drug Administration.These products are not intended to diagnose, treat, cure, or prevent any disease. Clinical data onfile & individual results may vary.
​
​